Fgf13 cancer
WebFibroblast growth factor homologous factors (FHFs) belong to the fibroblast growth factor (FGF) superfamily, which plays an important role in prostate cancer (PCa). Mining of public database suggests that FGF13 (FHF2) mRNA expression is altered in … WebFGF13, a member of the FGF subfamily, has been found to be highly expressed in cancer cells such as prostate cancer, melanoma, glioma and multiple myeloma. However, the …
Fgf13 cancer
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WebCancers. A variation (polymorphism) in the FGFR4 gene that causes a switch in amino acids (the building blocks of proteins) is associated with several types of cancer, such as those that occur in the breast, colon, head and neck, and prostate. In people with this polymorphism, glycine is replaced by arginine at position 388 in the protein's chain of … Web中国科学院上海生命科学研究院植物生理生态研究所合成生物学重点实验室
WebExpression of FGF13 in cancer - Summary - The Human Protein Atlas FGF13 PATHOLOGY CANCER Dictionary Human pathology PROGNOSTIC SUMMARYi Gene … WebFunctional assays indicated that FGF9 protein synthesis was normally controlled by uORF-mediated translational repression, which kept the protein at a low level, but was upregulated in response to hypoxia through a switch to IRES-dependent translational control. Our data demonstrate that FGF9 IRES functions as a cellular switch to turn FGF9 ...
WebSep 17, 2024 · Researchers found that FGF13 enables precancerous cells to escape apoptosis during oncogenesis 12 and promotes the migration and invasion of triple … WebFGF13 A gene on chromosome Xq26.3 that encodes fibroblast growth factor 13 of the FGF family, which bind heparin and have a broad range of cellular activities, including cell …
WebProstate cancer is the second leading cause of cancer death in males in the United States. Metastatic prostate cancer has a five-year survival rate of 31%. Although many genes involved in prostate tumor development have been identified, the exact role that they play in tumor progression or metastasis is unclear. CD82, a
WebJan 12, 2024 · FGF13 is shown to act within the nucleolus by suppressing ribosomal RNA synthesis. It is proposed that FGF13 exerts a protective effect by dampening protein synthesis in tumor cells that are proliferating … breaches logoWebJan 4, 2024 · PIM1 is a serine/threonine kinase that promotes and maintains prostate tumorigenesis. While PIM1 protein levels are elevated in prostate cancer relative to local disease, the mechanisms by which ... breaches la giWebThe up-regulation of miR-10b suppressed the growth, colony formation, migration and invasion of CRC cell. Furthermore, the xenograft model indicated that miR-10b inhibited CRC cell growth and lung metastasis in vivo by targeting fibroblast growth factor 13 (FGF13). In addition, we demonstrated that the overexpression of FGF13 rescued the ... corwen station newsWebDec 1, 2024 · Qualitative ribosome alterations and cancer. ... (FGF13), a nucleolar protein overexpressed in lung cancer and melanoma, lowers the excessive rate of ribosome biogenesis during transformation and tumour progression to levels that are compatible with the protein homeostasis capacity [129]. The resulting decrease in proteotoxic stress … corwen swimming bathsbreaches meanWebSep 2, 2024 · Fibroblast growth factor 13 (FGF13) is aberrantly expressed in multiple cancer types, suggesting its essential role in tumorigenesis. Hence, we aimed to explore … breaches of article 8WebJan 15, 2024 · We previously showed that the autonomously upregulated product of fibroblast growth factor 13 gene ( FGF13; also known as FGF homologous factor 2 ( … breaches movie